Boric acid-impregnated silk fibroin/gelatin/hyaluronic acid-based films for improving the wound healing process

Basit Öğe Kaydı
dc.authoridAyça Bal Öztürk / 0000-0002-6502-528Xen_US
dc.authoridBurçin İzbudak / 0000-0002-5572-7966
dc.authorscopusidBurçin İzbudak / 57221779519en_US
dc.authorscopusidAyça Bal Öztürk / 57062000100en_US
dc.authorwosidAyça Bal Öztürk / M-4472-2018
dc.authorwosidBurçin Özbudak / GXP-7807-2022
dc.contributor.authorÖzen, Nurten
dc.contributor.authorÖzbaş, Zehra
dc.contributor.authorİzbudak, Burçin
dc.contributor.authorEmik, Serkan
dc.contributor.authorÖzkahraman, Bengi
dc.contributor.authorBal Öztürk, Ayça
dc.date.accessioned2021-10-12T10:26:42Z
dc.date.available2021-10-12T10:26:42Z
dc.date.issued2021en_US
dc.departmentİstinye Üniversitesi, Eczacılık Fakültesi, Eczacılık Temel Bilimleri Bölümüen_US
dc.description.abstractRecently, with the progression in wound dressings, the importance of the biocompatible material with enhanced features for potential applications in the biomedical field has been more developed. Current strategies focus on the acceleration of the wound healing by systematically designed dressing materials. In this study, biocompatible hydrogel films with the combination of silk fibroin, hyaluronic acid and gelatin biopolymers were fabricated. To gain the enhanced wound healing behavior of wound dressings, boric acid (BA) was formulated in various ratios. The prepared hydrogel films were characterized in terms of FTIR, TGA, DSC, and SEM analysis. Following to the swelling and mechanical tests, in vitro biocompatibility and wound healing tests were performed against L929 fibroblast cell line. Results suggest that the presence of 1% (wt/vol) BA in the formulation of silk fibroin/gelatin/hyaluronic acid based hydrogel films is the key in providing such an enhanced mechanical and wound healing feature and may offer an alternative approach for wound healing treatment. © 2021 Wiley Periodicals LLC.en_US
dc.identifier.citationÖzen, N., Özbaş, Z., İzbudak, B., (...), Özkahraman, B., Bal-Öztürk, A. (2021). Boric acid-impregnated silk fibroin/gelatin/hyaluronic acid-based films for improving the wound healing process. Journal of Applied Polymer Science. https://doi.org/10.1002/app.51715.en_US
dc.identifier.doi10.1002/app.51715en_US
dc.identifier.endpage9en_US
dc.identifier.issn0021-8995en_US
dc.identifier.scopus2-s2.0-85116110558en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.1002/app.51715
dc.identifier.uri1097-4628
dc.identifier.urihttps://hdl.handle.net/20.500.12713/2136
dc.identifier.wosWOS:000702878900001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorİzbudak, Burçin
dc.institutionauthorBal Öztürk, Ayça
dc.language.isoenen_US
dc.publisherJournal of Applied Polymer Scienceen_US
dc.relation.ispartofWileyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDifferential Scanning Calorimetryen_US
dc.subjectFilmsen_US
dc.subjectMechanical Propertiesen_US
dc.subjectThermogravimetric Analysisen_US
dc.titleBoric acid-impregnated silk fibroin/gelatin/hyaluronic acid-based films for improving the wound healing processen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
207.pdf
Boyut:
3.56 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Eczacılık Temel Bilimleri Bölümü Makale Koleksiyonu
Kök Hücre ve Doku Mühendisliği Programı Makale Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu