Evaluation of cerebral blood flow alterations and acute neuronal damage due to water-pipe smoking

Basit Öğe Kaydı
dc.authoridUygar Utku / 0000-0003-1280-4754
dc.authorscopusidUygar Utku / 26031792300
dc.authorwosidUygar Utku / EBP-6296-2022
dc.contributor.authorKarakayalı, Onur
dc.contributor.authorUtku, Uygar
dc.contributor.authorYılmaz, Serkan
dc.date.accessioned2020-08-30T20:06:57Z
dc.date.available2020-08-30T20:06:57Z
dc.date.issued2019
dc.departmentİstinye Üniversitesi, Sağlık Hizmetleri Meslek Yüksekokulu, Elektronörofizyoloji Bölümüen_US
dc.description.abstractBackground: Although water-pipe smoking is a great public health problem, data regarding the acute and chronic effects and the degree of toxin exposure are limited. While water pipe-related malignancy, pulmonary. infectious, cardiac effects, infertility, and biological effects have been described in a meta-analysis. there are no studies in the literature about its neurologic effects. Aims: To evaluate water pipe-related acute neurological effects and cerebral blood flow through transcranial Doppler ultrasonography and serum S100 calcium binding protein calcium binding protein level measurements. Study Design: Prospective observational study. Methods: Vital signs and baseline carboxyhemoglobin and S100 calcium binding protein levels, cerebral flood changes with transcranial Doppler ultrasound were evaluated and recorded before and after water-pipe smoking. Results: The mean age of the 31 volunteers was 30.61 (+/- 5.67) years and 24 of them (77.42%) were male. A statistically significant difference was determined in heart rate, oxygen saturation, systolic and diastolic arterial pressure values before and after water-pipe smoking (p<0.001, p=0.035, p=0.009, p=0.021, respectively). Mean carboxyhemoglobin level was 2.68% (+/- 1.68) before, 14.97% (+/- 4.83) after water-pipe smoking (p<0.001). The S100 calcium binding protein level was 25.05 mu/mL (+/- 8.34) at the beginning, 40.71 mu/mL (+/- 14.06) after water-pipe smoking (p<0.001). An increase was determined in peak, and median middle, anterior and posterior cerebral artery blood flow rates, and a decrease was determined in both the pulsatility index and resistivity index values after water-pipe smoking using transcranial Doppler ultrasound. Conclusion: Cerebral vasodilation develops due to the increase in cerebral blood flow rate and the decrease in pulsatility index, resistivity index values, and the elevation in carboxyhemoglobin, S100 calcium binding protein level indicates that water-pipe smoking leads to neuronal damage in the acute period.en_US
dc.identifier.citationKarakayalı, O., Utku, U., & Yılmaz, S. (2019). Evaluation of Cerebral Blood Flow Alterations and Acute Neuronal Damage due to Water-Pipe Smoking. Balkan medical journal, 36(2), 106.en_US
dc.identifier.doi10.4274/balkanmedj.galenos.2018.2018.0704en_US
dc.identifier.endpage112en_US
dc.identifier.issn2146-3123en_US
dc.identifier.issn2146-3131en_US
dc.identifier.issue2en_US
dc.identifier.pmid30396875en_US
dc.identifier.scopus2-s2.0-85062166642en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage106en_US
dc.identifier.trdizinid318786en_US
dc.identifier.urihttps://doi.org/10.4274/balkanmedj.galenos.2018.2018.0704
dc.identifier.urihttps://hdl.handle.net/20.500.12713/662
dc.identifier.volume36en_US
dc.identifier.wosWOS:000459455900006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUtku, Uygaren_US
dc.language.isoenen_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute Injuryen_US
dc.subjectCarboxyhemoglobinen_US
dc.subjectCerebral Blood Flowen_US
dc.subjectS100 Proteinsen_US
dc.subjectWater Pipe Smokingen_US
dc.titleEvaluation of cerebral blood flow alterations and acute neuronal damage due to water-pipe smokingen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
H21.pdf
Boyut:
5.43 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Elektronörofizyoloji Programı Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu